Clinical Trials

Open Clinical Trials

HIC Number 0805003786

Full TitleA Phase 1/2 Study of XL184 with or without Erlotinib in Subjects with Non-Small Cell Lung Cancer
Trial TypeTherapeutic
DiseaseNSCL
PIScott Gettinger 
Primary ObjectiveA Phase 1/2, open-label, safety and efficacy study. Phase 1 will follow a dose-escalation design and Phase 2 will employ an optimal Simon 2-stage design for each of two arms to which subjects will be randomly assigned. 
Target PopulationSubjects must have histologically confirmed NSCLC and currently have Stage IIIb or IV NSCLC. 
ExclusionPhase 1 only: the subject has received anti-cancer treatment 
FDA PhaseI-II 

For further information on this clinical trial, please call the Yale Cancer Center Clinical Trials Office at 203-785-5702.